Design and Analysis Core Director

Contact information:
Biostatistics
University of Minnesota
MMC 8303, Del Code 8303
420 Delaware St. SE
Minneapolis, MN 55455
Office: (612) 624-9963
chap@biostat.umn.edu

Chap Le was awarded his Doctorate from the University of New Mexico in Statistics. He is the Design and Analysis Core Director for the Transdisciplinary Tobacco Use Research Center (TTURC) at the University of Minnesota. He is also the Director of Biostatistics for the University of Minnesota Comprehensive Cancer Center. Dr. Le's major areas of research are cancers and tobacco use. His methodological interests include epidemiological methods, crossover designs, survival analysis, correlate binary data, ordered alternatives, ROC curves, and statistical methods for translational research.

Dr. Le also teaches “Statistics for Translational and Clinical research” in the Division of Biostatistics of the School of Public Health at the University of Minnesota. In 2001, he received the Leonard M. Schuman Award for Excellence in Teaching and the award for Outstanding Contributions to Post-Baccalaureate, Graduate and Professional Education. Throughout his career at the University of Minnesota, he has been designated as Distinguished Teaching Professor of Biostatistics.

Selected Recent Publications

1. Le CT. A solution for the most basic optimization problem associated with an ROC curve. Statistical Methods in Medical Research (in press, 2007).
   
   
2. Le CT and Grambsch PM. Design and analysis of In Vitro experiments for combination chemotherapy. Journal of Biopharmaceutical Statistics 2005;15(1):179-186.
   
   
3. Le CT, Grambsch PM, and Liu A. Estimation of cancer drug potencies and relative potencies from In Vitro data. Journal of Biopharmaceutical Statistics 2005;15(6): 903-912.
   
   
4. Hatsukami DK, Kotlyar M, Allen S, Jensen J, Li S, Le C, and Murphy S. Effects of cigarette reduction on cardiovascular risk factors and subjective measures. Chest. 2005;128(4):2528-2537.
   
   
5. Hecht SS, Murphy SE, Carmella SG, Li S, Jensen J, Le C, Joseph AM, and Hatsukami DK. Similar uptake of lung carcinogens by smokers of regular, light, and ultralight cigarettes. Cancer Epidemiology, Biomarkers and Prevention. 2005;14(3):693-698.
   
   
6. Le CT. Statistical Methods for the Comparison of Crossing Survival Curves. Chapter 15, in Handbook of Statistics, Volume 23: Survival Analysis, edited by N. Balakrishnan and C. R. Rao. Elsevier B.V., 2004.